Medical Weight Loss in Newport Beach
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If you’re having trouble losing weight, even with diet and exercise, we can help. At PCH MedSpa, the Newport Beach Wellness and Weight Loss pioneer clinic, we offer plans that combine the newest treatments with expert help so you can lose weight and keep it off.
Stop struggling with weight loss! We offer a proven healthy weight loss management path to success, combining cutting-edge treatments with personalized support. We will work closely with you to help you reach your goals in your weight loss journey.
Our approach to weight loss in Newport Beach CA, Southern California, is different. We use the latest science and a whole-body approach to ensure you get the best care.
Our team of doctors, nurses, and wellness experts will examine your health history, lifestyle, and weight loss goals. We take a comprehensive, science-backed approach, considering your unique health profile, lifestyle, and goals.
Our expert team develops a personalized plan to address all aspects of weight loss—from hormones and metabolism to lifestyle and habits—ensuring long-term success and improved well-being.
Important Clinical Research Notice
Disclaimer: PCH MedSpa does not sell, compound, or commercially dispense Retatrutide. The content on this page is strictly for educational and informational purposes. PCH MedSpa does not host clinical trials or provide pre-screening evaluations for this medication. Please consult with our qualified healthcare team to discuss the FDA-approved weight management therapies currently available at our practice.
Our "Weight Loss Newport Beach" Program Services:
GLP-1 Therapy:
We use the newest medicines like Semaglutide and Tirzepatide to control your appetite, manage your blood sugar, and help you lose weight. These medicines copy a natural hormone in your body that controls hunger and digestion.
- Semaglutide and Tirzepatide are very effective GLP-1 medicines. They make you feel less hungry, make you feel full longer, and slow down how quickly food leaves your stomach. This helps you lose weight and can also help people with type 2 diabetes manage their blood sugar. These medications have demonstrated significant results in clinical trials, leading to substantial and sustainable weight loss for many individuals.
Lipotropic Injections:
Lipotropic injections contain a specialized blend of vitamins, amino acids, and compounds that help your body metabolize fat more efficiently. Our medical-grade formula includes:
- Methionine, Inositol & Choline (MIC) – Essential compounds that help break down fat
- Vitamin B12 – Boosts energy and supports metabolism
- L-Carnitine – Aids in converting fat into energy
- B-Complex Vitamins – Support overall metabolic function
Peptide Therapy:
These new treatments can help you lose fat and build muscle. Peptides can help your body release growth hormone, which helps you lose fat, build muscle, recover from exercise faster, and feel more energetic. These therapies offer a targeted approach to improving body composition and overall vitality.
Biote Hormone Pellet Therapy:
Get your hormones back in balance to help you lose weight. As you get older, your hormone levels can change, which can make you gain weight and feel tired. Biote therapy uses hormones that are just like the ones your body makes to help you have more energy, feel better, build muscle, and burn fat. It’s safe, effective, and made just for you. This therapy can be particularly beneficial for those experiencing symptoms such as fatigue, decreased libido, and mood swings, which can hinder weight loss efforts.
Personalized Weight Loss Coaching:
Our weight loss experts will give you the support and advice you need to make healthy changes that last. We’ll help you overcome problems, develop good habits, and learn to enjoy healthy food. Our coaches provide ongoing support, accountability, and motivation to help you stay on track and make sustainable lifestyle changes. We address not only nutritional needs but also behavioral and emotional aspects of eating.
Medical Prescriptions:
If needed, we can offer prescriptions like Phentermine to help with your weight loss. These weight loss medications can reduce your appetite and increase your metabolism, but they work best when combined with a healthy diet, regular exercise, and lifestyle changes. Our doctors will review your health history to ensure these medicines are safe for you, and we’ll monitor you closely. We also provide comprehensive guidance on how to incorporate these medications into a broader weight management plan.
Body Toning With HIFEM (I-Shape NEMSCULPT):
Our I-Shape NEMSCULPT technology uses strong muscle contractions to build muscle and reduce fat. This can help you tone your stomach, buttocks, and thighs. It’s a non-invasive way to improve your body shape. This technology offers a convenient and effective way to enhance muscle definition and reduce fat without surgery or downtime.
Vitamin Injections & NAD+ IV Infusions:
These treatments can increase your energy and improve your overall health. By giving your body important nutrients directly, you can feel more energized, improve your immune system, think more clearly, and help your body repair itself. These therapies can be particularly beneficial for those with nutrient deficiencies or those seeking to optimize their cellular function and overall well-being.
KYBELLA:
If you have extra fat under your chin, KYBELLA can help. This FDA-approved treatment uses a natural substance to destroy fat cells, giving you a better chin profile. The results are long-lasting. KYBELLA offers a targeted and permanent solution for reducing submental fullness, also known as a “”double chin,”” leading to a more defined and sculpted jawline.
Muscle Building & Weight Loss Peptide Plan in Newport Beach
Physician-directed peptide therapy protocol for accelerated fat loss, lean muscle development, and enhanced recovery at PCH MedSpa.
What is the 12-Week Peptide Plan? The 12-Week Peptide Plan at PCH MedSpa combines four synergistic peptides—Ipamorelin, Tesamorelin, BPC Wolverine, and AOD-9604—to accelerate fat loss, build lean muscle, and optimize recovery. This physician-supervised protocol stimulates natural growth hormone release and enhances fat metabolism without synthetic hormone side effects.

Our 12-Week Peptide Plan is designed for patients seeking significant body composition changes. This comprehensive protocol works at the cellular level to stimulate natural growth hormone release, enhance fat metabolism, accelerate tissue repair, and support lean muscle development—delivering results that diet and exercise alone cannot achieve.
Your 12-Week Program Includes:
- Ipamorelin12-Week Supply — Growth hormone release for fat burning & better sleep
- Tesamorelin12-Week Supply — Targets visceral belly fat specifically
- BPC Wolverine (BPC-157)12-Week Supply — Accelerates healing & reduces inflammation
- AOD-960412-Week Supply — Burns fat without affecting blood sugar
How Each Peptide Works for Weight Loss
Ipamorelin
Selective growth hormone secretagogue that stimulates natural GH release for enhanced fat burning, improved sleep quality, and increased energy without HGH side effects.
Tesamorelin
FDA-recognized GHRH analog clinically proven to reduce visceral abdominal fat while preserving lean muscle mass. Targets stubborn belly fat that resists diet.
BPC Wolverine
Advanced healing peptide (BPC-157) that accelerates tissue repair, reduces inflammation, and supports joint and muscle recovery for athletes and active patients.
AOD-9604
Modified HGH fragment that stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat storage) without affecting blood sugar or insulin levels.
12-Week Peptide Plan Benefits
Frequently Asked Questions About Peptide Therapy
Weight loss results vary by individual, but patients typically see significant body composition improvements over the 12-week program. Tesamorelin specifically targets visceral belly fat, while AOD-9604 enhances overall fat metabolism. Combined with proper nutrition and exercise, many patients lose 10-20+ pounds while building lean muscle mass. Dr. Karandish will set realistic expectations during your consultation based on your specific health profile.
When prescribed and monitored by a qualified physician like Dr. Karandish at PCH MedSpa, peptide therapy is considered safe for most adults. Peptides work with your body's natural systems rather than introducing synthetic hormones. Side effects are typically mild and temporary. A comprehensive medical evaluation determines if you're a good candidate for peptide therapy.
Yes, peptide therapy can often be combined with GLP-1 medications like Semaglutide or Tirzepatide for enhanced results. Dr. Karandish creates personalized protocols that may combine multiple therapies based on your specific goals. This combination approach can maximize fat loss while preserving muscle—addressing the "Ozempic face" concern many patients have with GLP-1 medications alone.
Most patients notice initial improvements within 2-4 weeks, including better sleep quality, increased energy, and improved workout recovery. Visible body composition changes—reduced body fat and increased muscle definition—typically become noticeable by weeks 6-8. The full 12-week protocol delivers optimal cumulative results.
BPC-157, nicknamed "Wolverine" for its remarkable healing properties, is a body protection compound derived from a protein in gastric juice. It accelerates healing of muscles, tendons, ligaments, and gut lining. Athletes and active individuals use it to recover faster from injuries and intense training while reducing inflammation throughout the body.
The 12-Week Peptide Plan at PCH MedSpa includes all four peptides plus physician supervision throughout the program. Pricing varies based on individual needs and dosing protocols. Contact PCH MedSpa at (949) 242-9166 or schedule a consultation for personalized pricing information.
Medically Reviewed by Dr. Kaveh Karandish, MD
Board-Certified in Internal Medicine and Aesthetic Medicine
PCH MedSpa, Corona del Mar, CA
The PCH Difference in Medical Weight Loss
We're not just a weight loss clinic—we're a complete transformation center combining medical expertise, cutting-edge technology, and comprehensive aesthetic services that competitors simply cannot replicate.
Important Clinical Research Notice
Disclaimer: PCH MedSpa does not sell, compound, or commercially dispense Retatrutide. The content on this page is strictly for educational and informational purposes. PCH MedSpa does not host clinical trials or provide pre-screening evaluations for this medication. Please consult with our qualified healthcare team to discuss the FDA-approved weight management therapies currently available at our practice.
Clinical Trial Opportunities (Retatrutide Pre-Screening)
PCH MedSpa provides specialized pre-screening and clinical evaluation pathways for candidates interested in Retatrutide Phase 3 clinical trials. This investigational triple-hormone receptor agonist (GLP-1 + GIP + Glucagon) represents the forefront of metabolic research, with published trial data demonstrating up to 28.7% mean weight loss. Connect with our clinical team to evaluate your research eligibility.
Board-Certified Physician Care
Dr. Kaveh Karandish personally oversees every weight loss program. With 15+ years of clinical experience and international recognition as an Endolift pioneer, you receive expert medical guidance—not a nurse practitioner or physician assistant running your care. True physician-led treatment from consultation through maintenance.
Integrated Body Contouring
Unlike clinics that only offer injections, we provide complete transformation: GLP-1 medications + non-surgical body sculpting (i-Shape, Muscle Max) + laser skin tightening (Endolift) + facial rejuvenation. Address weight loss AND aesthetic concerns in one location with synergistic treatments that deliver 30-40% faster results.
Personalized Treatment Plans
No cookie-cutter approaches. We customize medication type, dosage schedules, nutritional protocols, and body contouring combinations based on your unique metabolism, health history, lifestyle, and specific weight loss goals. Your transformation journey is as individual as you are.
Advanced Peptide Therapy
Beyond GLP-1s, we offer cutting-edge peptide therapy including Ipamorelin, CJC-1295, AOD-9604, and Tesamorelin for metabolic optimization, muscle preservation, enhanced fat burning, and growth hormone optimization. Ideal for patients seeking alternatives to traditional medications or maximum results through combination protocols.
Premium Newport Beach Experience
Located in beautiful Corona del Mar, our state-of-the-art 5,000 sq ft facility offers a luxurious, private environment with the VIP client experience standards you expect in Newport Beach. Concierge-level service, discreet consultations, and exclusive amenities in Orange County's most prestigious medical spa.
Complete Medical Support
Monthly physician check-ins, 24/7 medical support line, comprehensive lab monitoring, nutritional counseling, IV vitamin therapy, and hormone optimization. We support every aspect of your weight loss and wellness journey with continuous medical oversight—not just prescription refills.
"Ozempic Face" Prevention & Treatment
Prevent and reverse facial volume loss with our specialized treatments: dermal fillers (Radiesse, Sculptra), Salmon DNA rejuvenation, PRF therapy, and Endolift skin tightening. We're one of the only clinics proactively addressing this common GLP-1 side effect. Maintain a youthful, healthy appearance throughout your entire weight loss journey.
Metabolic Optimization Programs
Beyond weight loss, we optimize your thyroid function, hormone balance, vitamin levels, and metabolic markers for sustainable results. Our comprehensive approach addresses the root causes of weight gain—not just symptoms. Includes IV nutrient therapy, bioidentical hormone replacement (BioTE), and metabolic testing.
Investigational Joint Pain Observations
In published clinical trial data, Retatrutide has demonstrated up to a 75% reduction in osteoarthritis pain—a unique mechanism being evaluated in ongoing research. This makes clinical study screening ideal for candidates navigating concurrent weight optimization objectives and chronic joint inflammation conditions.
Lifetime Weight Maintenance
We don't abandon you after you hit your goal weight. Our maintenance programs include ongoing medication management, quarterly body contouring sessions, nutritional check-ins, and metabolic monitoring. Sustain your results for life with our Weight Loss Maintenance Membership ($250-400/month).
Corporate Wellness Programs
Group discounts for companies and organizations. We offer on-site consultations, employee group programs, and outcomes tracking for Orange County businesses. Perfect for companies looking to reduce healthcare costs and improve employee wellness. 15-20% savings for groups of 5+.
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Experience the PCH MedSpa Difference
Schedule your free consultation with Dr. Karandish to discover how our comprehensive, physician-supervised approach delivers superior results that other clinics simply cannot match. Transform your life with Orange County's most advanced medical weight loss program.
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Why Choose PCH MedSpa, Newport Weight Loss Clinic?
Personalized Approach:
We create plans that are specifically designed for you.
Medical Expertise:
Our experienced medical team will make sure you are safe and get the best results.
Newest Technology:
We use the most advanced treatments for weight loss and body shaping.
Support Every Step Of The Way:
We provide ongoing support and education to help you succeed. We offer a supportive and encouraging environment to help you stay motivated and achieve your goals.
Focus On Results:
We are dedicated to helping you reach your weight loss goals. We are committed to providing you with the tools and resources you need to achieve lasting success.
Great Location:
We are located in Newport Beach.
Start Your Journey to a New You! Schedule Your Consultation Today!
Individual results may vary. Talk to our medical professionals to find out the best treatment options for you.





